Cephalexin (pronounced phonetically as sef-a-LEX-in) is a cephalosporin, which is a type of antibiotic similar to penicillin and amoxicillin. Cephalexin is a first-generation cephalosporin (the second and third generations are reserved for more serious infections). It’s most commonly used as a treatment for bacterial skin infections in dogs and sometimes off-label to treat UTIs or other types of bacterial infections in dogs and cats. Common brand names include Keflex, Rilexine, Daxbia, and Vetolexin.
If your dog has an allergy or sensitivity to cephalosporins, they should not be treated with cephalexin. Similarly, if your dog is sensitive to any other type of major antibiotics like penicillin, they shouldn’t receive cephalexin. Pregnant dogs or dogs that have certain conditions like kidney issues should be closely monitored.
Commonly, antibiotics are prescribed for bacterial infections. However, the specific antibiotic that your veterinarian chooses will depend on several factors, including the type of infection. Cephalexin is especially useful against Staphylococcal infections (most skin infections). It may also be used for:
Cephalexin is considered a broad-spectrum antibiotic that is useful in many types of uncomplicated infections. It is effective against several different types of gram-positive (Trusted Source) and some gram-negative bacteria (Trusted Source) , and is able to withstand the anti-penicillin enzymes produced by Staphylococci. If your dog has a complex infection your vet may recommend a bacterial culture to grow the specific type of bacteria present and determine which antibiotics it will respond to. In general, cephalexin is a good choice against the following:
Cephalexin is normally prescribed orally as capsules, tablets, or chewables. If your dog has a hard time swallowing solid medication, there are liquid forms or injectable forms available.
The dosage is highly dependent on the type of infection your dog has, how serious it is, and where it’s located within your dog, as well as factors such as your dog’s weight, age, and overall health. Never give your dog any expired or leftover medication from another pet or person. Follow your veterinarian’s directions closely and never give your pet more than the recommended dose. Even if your pet seems to be feeling better, you need to finish the complete course of medication prescribed.
👉 It’s of the utmost importance that you use these antibiotics appropriately. Misuse can cause the growth of antibiotic-resistant bacteria, causing the infection to come back stronger and requiring stronger antibiotics.
In the case that you forget to administer a dose, give it to your dog as soon as you remember. However, if you’re very close to your dog’s next dose, don’t administer a double dose. Following this, continue with your normal schedule.
Antibiotics are usually well-tolerated by most dogs and cephalexin itself has a low risk of any negative side effects. Dogs do sometimes react with vomiting, diarrhea, or a change in appetite. If you notice these symptoms, contact your vet for advice on how to reduce these effects. It may help to give the medication with food.
According to betterpet veterinarian Dr. Liza Cahn, it’s rare for dogs to have an allergic reaction to cephalexin. But, she states that “if you notice hives, facial swelling, difficulty breathing, and vomiting, seek veterinary care immediately.”
Infections can be uncomfortable for your dog, and seeking appropriate care is necessary for getting them back on track to health. Cephalexin can be a great option for treatmenting bacterial infections so talk with your vet about options.
As with any antibiotic, your dog should take their full prescription, but it can take up to 48 hours to start seeing any improvements in their condition.
Your dog may be prescribed medication for anywhere from seven to 28 days, or longer for certain types of infections.
If possible, store cephalexin in its original container. If you’re unable to do so, keep it in a closed container at room temperature away from moisture, excessive heat, and sunlight. The liquid form should be kept refrigerated and any excess should be discarded after 14 days.
While cephalexin is the same medication for dogs and humans, you should never give your dog any prescription medication without your vet’s guidance and approval.
Cephalexin is only available by prescription, so you’ll need to talk to your vet to determine if it’s the right choice.
